The high shear action of the Silverson rotor/stator workhead can rapidly mill both solid and semi-solid materials to a low micron size in a single operation. In this demonstration pistachio nuts complete with their shells are rapidly disintegrated to form a homogeneous paste. This is an application increasingly used in the preparation of samples for aflatoxin testing. Here crystals are rapidly milled to reduce their particle size. The degree of size reduction will depend on the hardness of the product, but for many applications, the use of a Silverson mixer will dispense with the need for conventional size-reduction equipment.